I am in the process of going from the stock V2 seat to a comfort.
For all reference purposes, I have had a chance to sit on both comfort and race seat, same bike, same place, back to back. For what is worth, it is not only the padding that is different between all these, but it is the shape (read slope) of the seat as well.
If you look at the seats from the side you will notice how the stock seat just point downward and makes you slide (even more) onto the tank than desired.
The comfort seat "flattens" out a bit and makes you not slide down as easily. Kind of like a V4 seat. Which I also think is a perfect seating position personally. But that is comparing apples to oranges, so I digress.
Then after the comfort seat I put the race seat on and although somewhat similar shape to it, the padding was non existent and was like beef jerky rough on the edges.
I tend to and find myself pushing myself off the tank more than desired within a ride. Considering all these variables play like a domino, soon you notice your wrists tend to get numb, maybe your hip/knee needs to pop back out and so on and so forth...