Yes there is a big difference in height of that tire.
The SC2 200/60 slick is right at 1 inch larger in circumference than the SP stock 200/55, and that slick grows a lot more as speed increases, which will throw off your overall gear ratio.
I run 15/42 gear ratio, and it doesn't quite get the bike back to the stock ratio with the stock tires, but it helps. A 43 rear gear probably would be perfect with the SC2 slick, but that will have to wait till next year.
But, they are great tires, I run them over everything else.
Good Luck
I run 26lbs hot (175 degrees F) on the SC2,
Approximately 19lbs cold before tire warmers,