In the last 2 years I have owned...
2022 Panigale V4 base (full exhaust and Mag wheels)
2016 Multi 1200 Pikes Peak (Stock)
2023 Multi V4 Pikes Peak (Akrapovic Exhaust, Mag rear wheel (haven't found a front yet))
Hands down if you want a bike to do it all with comfort and nice electronic updates the V4 Pikes Peak is the best bike I've owned. The 2016 Pikes Peak is very good bike but a little unrefined after you have had a more modern bike. I did get a chance to demo a 1260 and thought it was quite a bit better than the 2016 1200. The power has better and more consistent and the quickshifter is a huge plus for me. I do not ride on anything that isn't paved so I could not tell you how the Multi's do off road.