Panigale V4S: 2021 vs 2024

Pinwheel · 2025-01-17T12:32:20-0800

I've been considering buying either a used '21 V4S or '24 V4S.

1) Were there any issues with the '21 model year for the V4S -- any things I should look out for?

2) What would be the main differences between the '21 and '24 V4S? Differences in the engine? Differences in the electronics and rider aides?

Thanks in advance!

BP PanigaleV4S · 2025-01-17T13:28:19-0800

There were changes in 2022, 2023 2024. Each model year sees changes. Bigger in 2022, less so in 2023 and 2024.

I suggest watching review videos of those model years to get an idea of the changes over the years.

In the V4 Panigale models, 2020, 2022 and 2025 probably saw the biggest changes.

In the US, 2021 was the last year for EU4 emissions, 2022+ is EU5 but outside of that there wasn't really ever a revision to the engine. Gearing (transmission) at some point. The water pumps suck on all of them. Really the only big issue with the V4.

baggerman · 2025-01-17T14:37:48-0800

I think the 22's and later got all the serious changes. Substantial ergonomics changes, they revised the rear header so it cooks you less, swingarm pivot was raised, expansion of riding modes, revised transmission, revised front subframe, 2nd rev of both the water and oil pumps. But then you get Euro 5 as BP mentions. Personally if I were flush with cash it would be a 2025.

SuperDomestique · 2025-01-17T17:40:45-0800

21 is probably about $20k. 22 is about $24k. 25 is $34k.

22 was “a second faster” on track than the previous generation. And the 25 is again “a second faster” than the 24. 25 is marginal gains considering the price difference. 21 → 22 is $4k/sec. 22 → 25 is $10k/sec.

Also don’t forget about bottom ends more than occasionally lunching themselves. But this issue may be sorted now that we know that 300V’s rapidly thinning viscosity is probably the main culprit. Running a more stable oil like Redline or Maxima seems to be the solution.

Panigale V4S: 2021 vs 2024

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