Different flywheels gives Ducati the ability to fine tune engine braking and acceleration requirements. On the i4 the crankshaft is too wide. The basics of a MotoGP (or any bike) are engine characteristics, the rest of the bike is built around that. The wide i4 is really stable, at 20,000 revs its generating all these gyroscopic forces that make it hard to flick but that also allows great corner speed whereas the v4 is very quick to turn and naturally favours point and shoot. Where Yamaha have lost their sweet handing advantage is through all the aero which allows the V4's to turn like an I4 i.e Aprilia which has the most advance aero behaves like the Yamaha of old. Ducati can change the flywheel weight to make the bike more flickable or more stable, its a huge advantage. In high school physics holding a bike wheel and playing with gyroscopic forces, its pretty incredible how the forces interact so imagine whats involved with a spinning mass of metal at 20k or more!