I think another important difference to note, are the obstacles they were built to endure. Simply put, I don't think the Pani R will have near the longevity of the 1299S, or the 1199 R. Sacrifices in durability had to of been made in designing a bike with such a singular focus. It makes me wonder if all the homologation hype surrounding it isn't solely a marketing strategy, but partly a disclosure statement. Its no secret how often race bikes are rebuilt.
Statements such as these only exacerbate that belief.
"The Panigale R is also fitted with a clutch designed specifically for racing as well as a series of technical features that ensure maximum performance even after long distances, considering the strict regulations on power unit quotas in races reserved for modified production bikes."
They state right off the bat the design focus, followed with a remark on how longevity was improved to reassure concerned consumers. What they don't disclose is the frame of reference to which "long distances" applies. Are we talking an endurance race, a race season, or 50,000 miles? I doubt its the latter.
The lightweight crank, flywheel, among other components might not be built for the stresses of a commuter bike. I'm not knocking the bike, it is the epitome of perfection in my opinion, but that doesn't make me any more confident concerning its durability.